SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jsp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTB_A_PZQA901_0 (GLUTATHIONE S-TRANSFERASE)	2jsp	TRANSCRIPTIONAL REGULATORY PROTEIN ROS (Agrobacterium tumefaciens)	3 / 3	GLN A 7 TYR A 49 ARG A 50	None	0.89A	1gtbA-2jspA: undetectable	1gtbA-2jspA: 15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_A_CUA601_0 (LACCASE-1)	2jsp	TRANSCRIPTIONAL REGULATORY PROTEIN ROS (Agrobacterium tumefaciens)	4 / 5	HIS A 42 CYH A 24 HIS A 37 LEU A 34	None	1.36A	3qpkA-2jspA: undetectable	3qpkA-2jspA: 9.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CCQ_A_ACTA1317_0 (THIOREDOXIN REDUCTASE)	2jsp	TRANSCRIPTIONAL REGULATORY PROTEIN ROS (Agrobacterium tumefaciens)	3 / 3	LEU A 73 GLU A 68 SER A 71	None	0.73A	4ccqA-2jspA: undetectable	4ccqA-2jspA: 12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WEA_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	2jsp	TRANSCRIPTIONAL REGULATORY PROTEIN ROS (Agrobacterium tumefaciens)	4 / 5	LEU A 55 LYS A 52 LEU A 25 GLU A 26	None	1.33A	5weaA-2jspA: undetectable	5weaA-2jspA: 7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GB9_A_ACTA508_0 (MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1)	2jsp	TRANSCRIPTIONAL REGULATORY PROTEIN ROS (Agrobacterium tumefaciens)	3 / 3	VAL A 23 ALA A 10 GLN A 18	None	0.67A	6gb9A-2jspA: undetectable	6gb9A-2jspA: 9.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTB_A_PZQA901_0","GLUTATHIONE S-TRANSFERASE","2jsp","TRANSCRIPTIONAL REGULATORY PROTEIN ROS","Agrobacterium tumefaciens",3,"GLN A   7;TYR A  49;ARG A  50","None","0.89A","1gtbA-2jspA:undetectable","1gtbA-2jspA:15.96"],["3QPK_A_CUA601_0","LACCASE-1","2jsp","TRANSCRIPTIONAL REGULATORY PROTEIN ROS","Agrobacterium tumefaciens",4,"HIS A  42;CYH A  24;HIS A  37;LEU A  34","None","1.36A","3qpkA-2jspA:undetectable","3qpkA-2jspA:9.66"],["4CCQ_A_ACTA1317_0","THIOREDOXIN REDUCTASE","2jsp","TRANSCRIPTIONAL REGULATORY PROTEIN ROS","Agrobacterium tumefaciens",3,"LEU A  73;GLU A  68;SER A  71","None","0.73A","4ccqA-2jspA:undetectable","4ccqA-2jspA:12.70"],["5WEA_A_IPHA901_0","PROTEIN ARGONAUTE-2","2jsp","TRANSCRIPTIONAL REGULATORY PROTEIN ROS","Agrobacterium tumefaciens",4,"LEU A  55;LYS A  52;LEU A  25;GLU A  26","None","1.33A","5weaA-2jspA:undetectable","5weaA-2jspA:7.02"],["6GB9_A_ACTA508_0","MOLYBDOPTERIN BIOSYNTHESIS PROTEIN CNX1","2jsp","TRANSCRIPTIONAL REGULATORY PROTEIN ROS","Agrobacterium tumefaciens",3,"VAL A  23;ALA A  10;GLN A  18","None","0.67A","6gb9A-2jspA:undetectable","6gb9A-2jspA:9.77"]]