SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		4 / 7 ALA A 128
SER A 130
VAL A  51
LEU A 127
 None
 0.77A 3o14A-2jszA:
undetectable		 3o14A-2jszA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		5 / 10 ALA A 143
GLY A 118
PRO A  25
ALA A  24
VAL A 140
 None
 0.93A 3t3cB-2jszA:
undetectable		 3t3cB-2jszA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		3 / 3 ASP A  61
ARG A  65
ASP A  56
 None
 0.71A 4fp9A-2jszA:
undetectable		 4fp9A-2jszA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		3 / 3 ASP A  61
ARG A  65
ASP A  56
 None
 0.73A 4fp9C-2jszA:
undetectable		 4fp9C-2jszA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		3 / 3 ASP A  61
ARG A  65
ASP A  56
 None
 0.70A 4fp9F-2jszA:
undetectable		 4fp9F-2jszA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		3 / 3 LEU A  30
MET A 111
TYR A  80
 None
 0.96A 4p6xG-2jszA:
undetectable		 4p6xG-2jszA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		3 / 3 TRP A  93
ILE A  52
SER A  83
 None
 0.92A 5gqbA-2jszA:
undetectable		 5gqbA-2jszA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 2jsz PROBABLE THIOL
PEROXIDASE
(Bacillus
subtilis) 		4 / 5 PRO A  10
GLY A   9
THR A   5
LYS A   7
 None
 1.23A 5x23A-2jszA:
undetectable		 5x23A-2jszA:
16.70