SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ju1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		4 / 6 HIS A  80
LEU A  64
LEU A  72
PRO A  73
 None
 1.19A 1hz4A-2ju1A:
undetectable		 1hz4A-2ju1A:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE9_A_VDXA500_1
(VITAMIN D3 RECEPTOR)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU A  21
LEU A  24
VAL A  25
SER A  28
HIS A  80
 None
 1.31A 1ie9A-2ju1A:
undetectable		 1ie9A-2ju1A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ALA A  66
LEU A   9
ARG A   6
LEU A  21
THR A  27
 None
 1.45A 2aa6B-2ju1A:
undetectable		 2aa6B-2ju1A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ALA A  66
LEU A   9
ARG A   6
LEU A  21
THR A  27
 None
 1.41A 2oaxC-2ju1A:
undetectable		 2oaxC-2ju1A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ALA A  66
LEU A   9
ARG A   6
LEU A  21
THR A  27
 None
 1.46A 2oaxF-2ju1A:
undetectable		 2oaxF-2ju1A:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		3 / 3 LEU A  12
PRO A  13
ARG A  23
 None
 0.66A 2qd4B-2ju1A:
undetectable		 2qd4B-2ju1A:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M7R_A_VDXA425_1
(VITAMIN D3 RECEPTOR)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		5 / 12 LEU A  21
LEU A  24
VAL A  25
SER A  28
HIS A  80
 None
 1.13A 3m7rA-2ju1A:
undetectable		 3m7rA-2ju1A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		5 / 12 ALA A  66
LEU A   9
ARG A   6
LEU A  21
THR A  27
 None
 1.39A 3vhuA-2ju1A:
undetectable		 3vhuA-2ju1A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2ju1 ERYTHRONOLIDE
SYNTHASE
(Saccharopolyspor
a
erythraea) 		4 / 8 ALA A  83
VAL A  86
LEU A  76
VAL A  32
 None
 0.75A 5nujA-2ju1A:
undetectable		 5nujA-2ju1A:
22.94