SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jug'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA1_1
(CES1 PROTEIN)		 2jug TUBC PROTEIN
(Archangium
disciforme) 		5 / 12 GLY A  46
GLY A  47
LEU A  21
LEU A  55
HIS A  50
 None
 1.02A 1ya4A-2jugA:
undetectable		 1ya4A-2jugA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 2jug TUBC PROTEIN
(Archangium
disciforme) 		5 / 12 LEU A  52
ALA A  54
LEU A  11
LEU A  10
GLY A  18
 None
 1.04A 3olsA-2jugA:
undetectable		 3olsA-2jugA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 2jug TUBC PROTEIN
(Archangium
disciforme) 		5 / 12 LEU A  52
ALA A  54
LEU A  11
LEU A  10
GLY A  18
 None
 1.00A 3q95A-2jugA:
undetectable		 3q95A-2jugA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 2jug TUBC PROTEIN
(Archangium
disciforme) 		5 / 11 LEU A  52
ALA A  54
LEU A  11
LEU A  10
GLY A  18
 None
 0.99A 3uudA-2jugA:
undetectable		 3uudA-2jugA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 2jug TUBC PROTEIN
(Archangium
disciforme) 		5 / 12 LEU A  52
ALA A  54
LEU A  11
LEU A  10
GLY A  18
 None
 0.98A 4pxmA-2jugA:
undetectable		 4pxmA-2jugA:
16.54