SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jv3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
2jv3 ETS1 PROTO-ONCOGENE
(Mus
musculus)
4 / 8 HIS A 128
ILE A 131
SER A  54
ALA A  84
None
0.92A 4eyzA-2jv3A:
undetectable
4eyzA-2jv3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)
2jv3 ETS1 PROTO-ONCOGENE
(Mus
musculus)
4 / 8 HIS A 128
ILE A 131
SER A  54
ALA A  84
None
0.92A 4eyzB-2jv3A:
undetectable
4eyzB-2jv3A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
2jv3 ETS1 PROTO-ONCOGENE
(Mus
musculus)
4 / 6 PHE A 113
VAL A  77
LEU A 132
LEU A 129
None
0.97A 6e43A-2jv3A:
undetectable
6e43A-2jv3A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
2jv3 ETS1 PROTO-ONCOGENE
(Mus
musculus)
4 / 6 PHE A 113
VAL A  77
LEU A 132
LEU A 129
None
0.92A 6e43B-2jv3A:
undetectable
6e43B-2jv3A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
2jv3 ETS1 PROTO-ONCOGENE
(Mus
musculus)
4 / 6 PHE A 113
VAL A  77
LEU A 132
LEU A 129
None
0.98A 6e43C-2jv3A:
undetectable
6e43C-2jv3A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)
2jv3 ETS1 PROTO-ONCOGENE
(Mus
musculus)
4 / 6 PHE A 113
VAL A  77
LEU A 132
LEU A 129
None
0.83A 6e43D-2jv3A:
undetectable
6e43D-2jv3A:
14.93