SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jv8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_C_DVAC6_0 (GRAMICIDIN A)	2jv8	UNCHARACTERIZED PROTEIN NE1242 (Nitrosomonas europaea)	3 / 3	ALA A 34 VAL A 31 TRP A 39	None	0.90A	1c4dC-2jv8A: undetectable 1c4dD-2jv8A: undetectable	1c4dC-2jv8A: 13.43 1c4dD-2jv8A: 13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_D_DVAD6_0 (GRAMICIDIN A)	2jv8	UNCHARACTERIZED PROTEIN NE1242 (Nitrosomonas europaea)	3 / 3	TRP A 39 ALA A 34 VAL A 31	None	0.91A	1c4dC-2jv8A: undetectable 1c4dD-2jv8A: undetectable	1c4dC-2jv8A: 13.43 1c4dD-2jv8A: 13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB6_0 (GRAMICIDIN A)	2jv8	UNCHARACTERIZED PROTEIN NE1242 (Nitrosomonas europaea)	3 / 3	ALA A 34 VAL A 31 TRP A 39	None	0.93A	1tkqB-2jv8A: undetectable	1tkqB-2jv8A: 18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID5_B_SAMB301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	2jv8	UNCHARACTERIZED PROTEIN NE1242 (Nitrosomonas europaea)	5 / 11	GLU A 6 PHE A 8 ALA A 56 ASP A 14 ILE A 23	None	1.35A	3id5B-2jv8A: undetectable	3id5B-2jv8A: 15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID5_F_SAMF301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	2jv8	UNCHARACTERIZED PROTEIN NE1242 (Nitrosomonas europaea)	5 / 11	GLU A 6 PHE A 8 ALA A 56 ASP A 14 ILE A 23	None	1.35A	3id5F-2jv8A: undetectable	3id5F-2jv8A: 15.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_C_DVAC6_0","GRAMICIDIN A","2jv8","UNCHARACTERIZED PROTEIN NE1242","Nitrosomonas europaea",3,"ALA A  34;VAL A  31;TRP A  39","None","0.90A","1c4dC-2jv8A:undetectable;1c4dD-2jv8A:undetectable","1c4dC-2jv8A:13.43;1c4dD-2jv8A:13.43"],["1C4D_D_DVAD6_0","GRAMICIDIN A","2jv8","UNCHARACTERIZED PROTEIN NE1242","Nitrosomonas europaea",3,"TRP A  39;ALA A  34;VAL A  31","None","0.91A","1c4dC-2jv8A:undetectable;1c4dD-2jv8A:undetectable","1c4dC-2jv8A:13.43;1c4dD-2jv8A:13.43"],["1TKQ_B_DVAB6_0","GRAMICIDIN A","2jv8","UNCHARACTERIZED PROTEIN NE1242","Nitrosomonas europaea",3,"ALA A  34;VAL A  31;TRP A  39","None","0.93A","1tkqB-2jv8A:undetectable","1tkqB-2jv8A:18.00"],["3ID5_B_SAMB301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","2jv8","UNCHARACTERIZED PROTEIN NE1242","Nitrosomonas europaea",5,"GLU A   6;PHE A   8;ALA A  56;ASP A  14;ILE A  23","None","1.35A","3id5B-2jv8A:undetectable","3id5B-2jv8A:15.95"],["3ID5_F_SAMF301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","2jv8","UNCHARACTERIZED PROTEIN NE1242","Nitrosomonas europaea",5,"GLU A   6;PHE A   8;ALA A  56;ASP A  14;ILE A  23","None","1.35A","3id5F-2jv8A:undetectable","3id5F-2jv8A:15.95"]]