SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jva'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_B_RTLB501_0
(RETINOL DEHYDRATASE)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ILE A  15
LEU A  48
SER A  46
LEU A  91
ILE A  95
 None
 1.25A 1fmlB-2jvaA:
undetectable		 1fmlB-2jvaA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 LEU A  72
LEU A  39
LEU A  17
LEU A   2
LEU A  94
 None
 1.17A 3d90B-2jvaA:
undetectable		 3d90B-2jvaA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ILE A  70
ILE A  43
ILE A  95
LEU A  59
HIS A 105
 None
 1.11A 3o1cA-2jvaA:
undetectable		 3o1cA-2jvaA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ILE A  70
ILE A  43
ILE A  95
LEU A  59
HIS A 105
 None
 1.10A 3o1xA-2jvaA:
undetectable		 3o1xA-2jvaA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 10 ILE A  70
ILE A  43
ILE A  95
LEU A  59
HIS A 105
 None
 1.09A 3qgzA-2jvaA:
undetectable		 3qgzA-2jvaA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 12 ILE A  95
ALA A  98
ALA A  99
LEU A  56
VAL A   8
 None
 1.04A 4k6iA-2jvaA:
undetectable		 4k6iA-2jvaA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 2jva PEPTIDYL-TRNA
HYDROLASE DOMAIN
PROTEIN
(Pseudomonas
syringae
group
genomosp.
3) 		5 / 11 LEU A  56
LEU A  10
LEU A   2
ILE A  15
LEU A  48
 None
 1.05A 4zowA-2jvaA:
undetectable		 4zowA-2jvaA:
16.22