SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB504_1
(YKOF)		 2jwp MALECTIN
(Xenopus
laevis) 		4 / 6 PRO A  33
PHE A 149
LEU A 153
ILE A  75
 None
 1.16A 1sbrA-2jwpA:
undetectable
1sbrB-2jwpA:
undetectable		 1sbrA-2jwpA:
21.95
1sbrB-2jwpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 2jwp MALECTIN
(Xenopus
laevis) 		5 / 7 ALA A  41
ASP A  32
GLY A  17
GLY A  18
ASN A  15
 None
 1.34A 2c49B-2jwpA:
undetectable		 2c49B-2jwpA:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 2jwp MALECTIN
(Xenopus
laevis) 		4 / 4 GLU A  19
GLY A  17
THR A  63
GLU A  64
 None
 0.93A 3e9xA-2jwpA:
undetectable		 3e9xA-2jwpA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 2jwp MALECTIN
(Xenopus
laevis) 		3 / 3 SER A  53
ASP A 116
ASP A 128
 None
 0.78A 4uckA-2jwpA:
undetectable		 4uckA-2jwpA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 2jwp MALECTIN
(Xenopus
laevis) 		4 / 8 ILE A 117
GLN A  98
VAL A 112
ASP A 128
 None
 1.04A 5vlmF-2jwpA:
undetectable		 5vlmF-2jwpA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 2jwp MALECTIN
(Xenopus
laevis) 		3 / 3 HIS A 109
ASN A 107
LEU A 153
 None
 0.82A 6f7lB-2jwpA:
undetectable		 6f7lB-2jwpA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 2jwp MALECTIN
(Xenopus
laevis) 		3 / 3 LYS A 113
VAL A 101
ASP A 103
 None
 0.71A 6fgdA-2jwpA:
undetectable		 6fgdA-2jwpA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 2jwp MALECTIN
(Xenopus
laevis) 		3 / 3 LYS A 136
SER A 141
SER A 134
 None
 1.12A 6gbfA-2jwpA:
undetectable		 6gbfA-2jwpA:
18.66