SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jww'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_D_FUAD705_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 12	SER A 71 PHE A 29 LEU A 35 VAL A 43 PHE A 102	None	1.48A	1q23D-2jwwA: undetectable 1q23E-2jwwA: undetectable	1q23D-2jwwA: 20.18 1q23E-2jwwA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_E_FUAE706_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 10	SER A 71 PHE A 29 LEU A 35 VAL A 43 PHE A 102	None	1.48A	1q23E-2jwwA: undetectable	1q23E-2jwwA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_G_FUAG708_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 11	SER A 71 PHE A 29 LEU A 35 VAL A 43 PHE A 102	None	1.49A	1q23G-2jwwA: 0.0	1q23G-2jwwA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_J_FUAJ711_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 11	SER A 71 PHE A 29 LEU A 35 VAL A 43 PHE A 102	None	1.39A	1q23J-2jwwA: undetectable	1q23J-2jwwA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_K_FUAK712_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 10	SER A 71 PHE A 29 LEU A 35 VAL A 43 PHE A 102	None	1.45A	1q23K-2jwwA: undetectable	1q23K-2jwwA: 20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_A_SAMA301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 12	LEU A 77 GLU A 101 GLY A 89 ASP A 90 ALA A 88	None	1.00A	2br4A-2jwwA: undetectable	2br4A-2jwwA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_E_SAME301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 12	LEU A 77 GLU A 101 GLY A 89 ASP A 90 ALA A 88	None	0.94A	2br4E-2jwwA: undetectable	2br4E-2jwwA: 19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_F_SAMF301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	2jww	PARVALBUMIN ALPHA (Rattus norvegicus)	5 / 12	LEU A 77 GLU A 101 GLY A 89 ASP A 90 ALA A 88	None	1.02A	2br4F-2jwwA: undetectable	2br4F-2jwwA: 19.09

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Q23_D_FUAD705_1","CHLORAMPHENICOL ACETYLTRANSFERASE;CHLORAMPHENICOL ACETYLTRANSFERASE","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"SER A  71;PHE A  29;LEU A  35;VAL A  43;PHE A 102","None","1.48A","1q23D-2jwwA:undetectable;1q23E-2jwwA:undetectable","1q23D-2jwwA:20.18;1q23E-2jwwA:20.18"],["1Q23_E_FUAE706_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"SER A  71;PHE A  29;LEU A  35;VAL A  43;PHE A 102","None","1.48A","1q23E-2jwwA:undetectable","1q23E-2jwwA:20.18"],["1Q23_G_FUAG708_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"SER A  71;PHE A  29;LEU A  35;VAL A  43;PHE A 102","None","1.49A","1q23G-2jwwA:0.0","1q23G-2jwwA:20.18"],["1Q23_J_FUAJ711_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"SER A  71;PHE A  29;LEU A  35;VAL A  43;PHE A 102","None","1.39A","1q23J-2jwwA:undetectable","1q23J-2jwwA:20.18"],["1Q23_K_FUAK712_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"SER A  71;PHE A  29;LEU A  35;VAL A  43;PHE A 102","None","1.45A","1q23K-2jwwA:undetectable","1q23K-2jwwA:20.18"],["2BR4_A_SAMA301_0","CEPHALOSPORIN HYDROXYLASE CMCI","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"LEU A  77;GLU A 101;GLY A  89;ASP A  90;ALA A  88","None","1.00A","2br4A-2jwwA:undetectable","2br4A-2jwwA:19.09"],["2BR4_E_SAME301_0","CEPHALOSPORIN HYDROXYLASE CMCI","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"LEU A  77;GLU A 101;GLY A  89;ASP A  90;ALA A  88","None","0.94A","2br4E-2jwwA:undetectable","2br4E-2jwwA:19.09"],["2BR4_F_SAMF301_0","CEPHALOSPORIN HYDROXYLASE CMCI","2jww","PARVALBUMIN ALPHA","Rattus norvegicus",5,"LEU A  77;GLU A 101;GLY A  89;ASP A  90;ALA A  88","None","1.02A","2br4F-2jwwA:undetectable","2br4F-2jwwA:19.09"]]