SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		3 / 3 GLN B 160
HIS B  25
ARG B 156
 None
HEC  B 250 (-3.7A)
None
 0.61A 1zlqA-2jxmB:
undetectable		 1zlqA-2jxmB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_C_SPMC1434_1
(NITROALKANE OXIDASE)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		5 / 12 LEU B 152
VAL B 104
ALA B 117
LEU B 116
LEU B  75
 None
 1.19A 2c12C-2jxmB:
undetectable		 2c12C-2jxmB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C12_F_SPMF1433_1
(NITROALKANE OXIDASE)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		5 / 11 LEU B 152
VAL B 104
ALA B 117
LEU B 116
LEU B  75
 None
 1.16A 2c12F-2jxmB:
undetectable		 2c12F-2jxmB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		4 / 6 GLY B 153
PHE B 236
LYS B  29
THR B  30
 None
HEC  B 250 ( 4.9A)
None
None
 1.35A 2m2oB-2jxmB:
undetectable		 2m2oB-2jxmB:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		5 / 12 THR B 105
GLY B 118
LEU B 103
MET B 128
VAL B  49
 None
HEC  B 250 ( 4.3A)
None
None
None
 1.14A 3fzgA-2jxmB:
undetectable		 3fzgA-2jxmB:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		5 / 12 GLY B 235
GLY B 157
ASN B 170
VAL B  71
GLU B  32
 None
HEC  B 250 (-3.4A)
None
HEC  B 250 (-4.1A)
None
 1.11A 3p2kB-2jxmB:
undetectable		 3p2kB-2jxmB:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		4 / 8 GLY B  17
THR B  16
GLN B 238
GLU B  14
 None
 0.95A 3rglA-2jxmB:
undetectable		 3rglA-2jxmB:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		4 / 6 GLY B 165
VAL B 161
PRO B 163
TYR B   4
 None
HEC  B 250 (-4.8A)
HEC  B 250 (-2.5A)
HEC  B 250 ( 4.7A)
 0.74A 4dxuA-2jxmB:
undetectable		 4dxuA-2jxmB:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		4 / 8 VAL B  51
ASN B 155
GLN B  59
MET B 128
 None
HEC  B 250 ( 4.7A)
HEC  B 250 (-4.1A)
None
 1.09A 4iilA-2jxmB:
undetectable		 4iilA-2jxmB:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		4 / 5 LEU B  75
ALA B  73
LEU B 115
VAL B  71
 None
None
None
HEC  B 250 (-4.1A)
 1.04A 5cr1A-2jxmB:
undetectable		 5cr1A-2jxmB:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		4 / 6 GLY B  80
GLU B  79
TYR B 148
ILE B 243
 None
 0.96A 5kmfA-2jxmB:
undetectable
5kmfC-2jxmB:
undetectable		 5kmfA-2jxmB:
20.27
5kmfC-2jxmB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 2jxm CYTOCHROME F
(Prochlorothrix
hollandica) 		5 / 12 LEU B  83
VAL B 104
ALA B  73
ALA B 117
GLY B 118
 None
None
None
None
HEC  B 250 ( 4.3A)
 1.03A 5tzoB-2jxmB:
undetectable		 5tzoB-2jxmB:
20.87