SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jxu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 2jxu TERB
(Klebsiella
pneumoniae) 		5 / 12 ALA A 134
LEU A 112
LEU A 151
PHE A 149
ALA A 139
 None
 0.89A 1bzfA-2jxuA:
undetectable		 1bzfA-2jxuA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_B_SALB4005_1
(XANTHINE
DEHYDROGENASE)		 2jxu TERB
(Klebsiella
pneumoniae) 		4 / 7 GLU A  65
PHE A  30
THR A  34
VAL A  35
 None
 0.91A 1fo4B-2jxuA:
undetectable		 1fo4B-2jxuA:
8.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 2jxu TERB
(Klebsiella
pneumoniae) 		4 / 7 THR A  12
ILE A  75
ASN A  79
PHE A  78
 None
 1.17A 2jc9A-2jxuA:
undetectable		 2jc9A-2jxuA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2jxu TERB
(Klebsiella
pneumoniae) 		4 / 8 MET A  56
PHE A  59
ALA A 102
LEU A 101
 None
 0.94A 2o01A-2jxuA:
undetectable		 2o01A-2jxuA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 2jxu TERB
(Klebsiella
pneumoniae) 		4 / 6 THR A  34
VAL A  35
LEU A  60
GLU A  65
 None
 1.27A 3b6rB-2jxuA:
undetectable		 3b6rB-2jxuA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_2
(HIV-1 PROTEASE)		 2jxu TERB
(Klebsiella
pneumoniae) 		4 / 7 ALA A  39
GLY A  33
ILE A  57
THR A  96
 None
 0.84A 3spkB-2jxuA:
undetectable		 3spkB-2jxuA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 2jxu TERB
(Klebsiella
pneumoniae) 		3 / 3 TYR A  99
MET A  31
LEU A  11
 None
 1.01A 3vw1D-2jxuA:
undetectable		 3vw1D-2jxuA:
23.38