SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 2jy9 PUTATIVE TRNA
HYDROLASE DOMAIN
(Salmonella
enterica) 		5 / 12 ILE A   2
PHE A  41
THR A  99
LEU A  48
ILE A   4
 None
 1.07A 1cd2A-2jy9A:
undetectable		 1cd2A-2jy9A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2jy9 PUTATIVE TRNA
HYDROLASE DOMAIN
(Salmonella
enterica) 		4 / 8 TYR A  52
LEU A  48
SER A  46
GLU A  14
 None
 0.81A 1i7zA-2jy9A:
undetectable		 1i7zA-2jy9A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2jy9 PUTATIVE TRNA
HYDROLASE DOMAIN
(Salmonella
enterica) 		5 / 12 ILE A  72
ALA A  74
GLN A  75
ALA A  36
ILE A  64
 None
 1.08A 3uvvB-2jy9A:
undetectable		 3uvvB-2jy9A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2jy9 PUTATIVE TRNA
HYDROLASE DOMAIN
(Salmonella
enterica) 		5 / 12 ILE A  72
ALA A  74
GLN A  75
ALA A  36
ILE A  64
 None
 1.12A 4nqaH-2jy9A:
undetectable		 4nqaH-2jy9A:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 2jy9 PUTATIVE TRNA
HYDROLASE DOMAIN
(Salmonella
enterica) 		5 / 12 ILE A   2
PHE A  41
THR A  99
LEU A  48
ILE A   4
 None
 1.06A 4p3qA-2jy9A:
undetectable		 4p3qA-2jy9A:
19.88