SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jyn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2jyn UPF0368 PROTEIN
YPL225W
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  34
ASN A 134
LEU A  44
PHE A 126
 None
 1.15A 1ru9H-2jynA:
undetectable
1ru9L-2jynA:
undetectable		 1ru9H-2jynA:
17.52
1ru9L-2jynA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 2jyn UPF0368 PROTEIN
YPL225W
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  34
ASN A 134
LEU A  44
PHE A 126
 None
 1.15A 1rukH-2jynA:
undetectable
1rukL-2jynA:
undetectable		 1rukH-2jynA:
17.52
1rukL-2jynA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2jyn UPF0368 PROTEIN
YPL225W
(Saccharomyces
cerevisiae) 		3 / 3 LYS A 135
ARG A  43
LYS A  95
 None
 1.46A 3okxA-2jynA:
undetectable		 3okxA-2jynA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 2jyn UPF0368 PROTEIN
YPL225W
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  96
ILE A 131
TYR A 127
GLU A 130
 None
 1.21A 4a99D-2jynA:
undetectable		 4a99D-2jynA:
16.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 2jyn UPF0368 PROTEIN
YPL225W
(Saccharomyces
cerevisiae) 		3 / 3 TRP A  85
GLU A  75
GLU A  61
 None
 0.81A 6fhwA-2jynA:
undetectable		 6fhwA-2jynA:
19.86