SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jz0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IA0_B_TXLB502_1 (TUBULIN BETA CHAIN)	2jz0	PROTEIN DOUBLESEX (Drosophila melanogaster)	5 / 12	VAL A 8 ASP A 7 ASP A 38 PRO A 3 GLY A 1	None	1.05A	1ia0B-2jz0A: undetectable	1ia0B-2jz0A: 10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TUB_B_TXLB501_1 (TUBULIN)	2jz0	PROTEIN DOUBLESEX (Drosophila melanogaster)	5 / 12	VAL A 8 ASP A 7 ASP A 38 PRO A 3 GLY A 1	None	1.05A	1tubB-2jz0A: undetectable	1tubB-2jz0A: 10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_A_EAAA212_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2jz0	PROTEIN DOUBLESEX (Drosophila melanogaster)	4 / 7	TYR A 12 PHE A 9 VAL A 8 GLY A 5	None	1.00A	3gssA-2jz0A: undetectable	3gssA-2jz0A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_B_EAAB211_1 (GLUTATHIONE S-TRANSFERASE P1-1)	2jz0	PROTEIN DOUBLESEX (Drosophila melanogaster)	4 / 7	TYR A 12 PHE A 9 VAL A 8 GLY A 5	None	1.00A	3gssB-2jz0A: undetectable	3gssB-2jz0A: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MX0_A_BCZA513_0 (NEURAMINIDASE)	2jz0	PROTEIN DOUBLESEX (Drosophila melanogaster)	5 / 12	LEU A 16 ARG A 47 SER A 45 ARG A 46 GLU A 42	None	1.01A	4mx0A-2jz0A: undetectable	4mx0A-2jz0A: 9.65

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1IA0_B_TXLB502_1","TUBULIN BETA CHAIN","2jz0","PROTEIN DOUBLESEX","Drosophila melanogaster",5,"VAL A   8;ASP A   7;ASP A  38;PRO A   3;GLY A   1","None","1.05A","1ia0B-2jz0A:undetectable","1ia0B-2jz0A:10.44"],["1TUB_B_TXLB501_1","TUBULIN","2jz0","PROTEIN DOUBLESEX","Drosophila melanogaster",5,"VAL A   8;ASP A   7;ASP A  38;PRO A   3;GLY A   1","None","1.05A","1tubB-2jz0A:undetectable","1tubB-2jz0A:10.10"],["3GSS_A_EAAA212_1","GLUTATHIONE S-TRANSFERASE P1-1","2jz0","PROTEIN DOUBLESEX","Drosophila melanogaster",4,"TYR A  12;PHE A   9;VAL A   8;GLY A   5","None","1.00A","3gssA-2jz0A:undetectable","3gssA-2jz0A:18.67"],["3GSS_B_EAAB211_1","GLUTATHIONE S-TRANSFERASE P1-1","2jz0","PROTEIN DOUBLESEX","Drosophila melanogaster",4,"TYR A  12;PHE A   9;VAL A   8;GLY A   5","None","1.00A","3gssB-2jz0A:undetectable","3gssB-2jz0A:18.67"],["4MX0_A_BCZA513_0","NEURAMINIDASE","2jz0","PROTEIN DOUBLESEX","Drosophila melanogaster",5,"LEU A  16;ARG A  47;SER A  45;ARG A  46;GLU A  42","None","1.01A","4mx0A-2jz0A:undetectable","4mx0A-2jz0A:9.65"]]