SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jzc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 2jzc UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		4 / 8 GLY A 194
PHE A  53
SER A 198
GLN A 199
 None
 1.04A 2a8tB-2jzcA:
undetectable		 2a8tB-2jzcA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RDD_A_AICA1110_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2jzc UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		4 / 4 LYS A  92
ALA A 104
PHE A 119
GLY A 118
 None
 1.25A 2rddA-2jzcA:
0.0		 2rddA-2jzcA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 2jzc UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		4 / 8 GLY A  36
PHE A  69
ILE A  66
PHE A  77
 None
 0.99A 3ko0O-2jzcA:
undetectable
3ko0Q-2jzcA:
undetectable		 3ko0O-2jzcA:
20.64
3ko0Q-2jzcA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 2jzc UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		3 / 3 HIS A 139
SER A 138
ARG A 216
 None
 0.98A 5u63A-2jzcA:
undetectable		 5u63A-2jzcA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 2jzc UDP-N-ACETYLGLUCOSAM
INE TRANSFERASE
SUBUNIT ALG13
(Saccharomyces
cerevisiae) 		4 / 8 PHE A  77
PHE A  69
VAL A  48
SER A  46
 None
 1.19A 6huoC-2jzcA:
undetectable
6huoD-2jzcA:
undetectable		 6huoC-2jzcA:
15.18
6huoD-2jzcA:
17.49