SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jzj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 2jzj CYANOVIRIN-N HOMOLOG
(Ceratopteris
richardii) 		4 / 6 PRO A  51
ASP A  44
ASN A  45
TYR A  50
 None
 1.41A 1hpkA-2jzjA:
undetectable		 1hpkA-2jzjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_A_SAMA226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2jzj CYANOVIRIN-N HOMOLOG
(Ceratopteris
richardii) 		5 / 12 GLY A  56
GLY A  42
GLY A  16
LEU A  70
ILE A  41
 None
 0.90A 3ku1A-2jzjA:
undetectable		 3ku1A-2jzjA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_C_SAMC226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2jzj CYANOVIRIN-N HOMOLOG
(Ceratopteris
richardii) 		5 / 12 GLY A  56
GLY A  42
GLY A  16
LEU A  70
ILE A  41
 None
 0.95A 3ku1C-2jzjA:
undetectable		 3ku1C-2jzjA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFM_A_CFFA330_1
(ADENOSINE RECEPTOR
A2A)		 2jzj CYANOVIRIN-N HOMOLOG
(Ceratopteris
richardii) 		4 / 7 VAL A  12
PHE A   5
LEU A  37
ILE A  35
 None
 1.00A 3rfmA-2jzjA:
undetectable		 3rfmA-2jzjA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRM_A_VD3A502_1
(VITAMIN D(3)
25-HYDROXYLASE)		 2jzj CYANOVIRIN-N HOMOLOG
(Ceratopteris
richardii) 		5 / 12 ILE A  41
LEU A  48
ALA A  72
ILE A  35
LEU A  14
 None
 1.06A 3vrmA-2jzjA:
undetectable		 3vrmA-2jzjA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS1_A_VORA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2jzj CYANOVIRIN-N HOMOLOG
(Ceratopteris
richardii) 		4 / 8 GLY A  56
THR A  62
LEU A  70
LEU A  88
 None
 0.85A 5hs1A-2jzjA:
undetectable		 5hs1A-2jzjA:
11.55