SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jzk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_A_DVAA6_0
(GRAMICIDIN A)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		3 / 3 ALA A  21
VAL A  31
TRP A  30
 None
 0.59A 1grmA-2jzkA:
undetectable		 1grmA-2jzkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GRM_B_DVAB6_0
(GRAMICIDIN A)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		3 / 3 ALA A  21
VAL A  31
TRP A  30
 None
 0.59A 1grmB-2jzkA:
undetectable		 1grmB-2jzkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_A_DVAA6_0
(GRAMICIDIN B)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		3 / 3 ALA A  21
VAL A  31
TRP A  30
 None
 0.78A 1jo3A-2jzkA:
undetectable		 1jo3A-2jzkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO3_B_DVAB6_0
(GRAMICIDIN B)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		3 / 3 ALA A  21
VAL A  31
TRP A  30
 None
 0.78A 1jo3B-2jzkA:
undetectable		 1jo3B-2jzkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_A_DVAA6_0
(GRAMICIDIN C)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		3 / 3 ALA A  21
VAL A  31
TRP A  30
 None
 0.65A 1jo4A-2jzkA:
undetectable		 1jo4A-2jzkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JO4_B_DVAB6_0
(GRAMICIDIN C)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		3 / 3 ALA A  21
VAL A  31
TRP A  30
 None
 0.65A 1jo4B-2jzkA:
undetectable		 1jo4B-2jzkA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 9 GLY A  16
LEU A  37
ASP A  36
ASN A  14
ILE A  41
 None
 1.35A 3wdmA-2jzkA:
undetectable		 3wdmA-2jzkA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  37
LEU A  71
GLU A  34
LEU A  19
LEU A  12
 None
 0.97A 4wg0B-2jzkA:
undetectable
4wg0C-2jzkA:
undetectable
4wg0D-2jzkA:
undetectable		 4wg0B-2jzkA:
19.05
4wg0C-2jzkA:
19.05
4wg0D-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  37
LEU A  71
GLU A  34
LEU A  19
LEU A  12
 None
 0.97A 4wg0D-2jzkA:
undetectable
4wg0E-2jzkA:
undetectable
4wg0F-2jzkA:
undetectable		 4wg0D-2jzkA:
19.05
4wg0E-2jzkA:
19.05
4wg0F-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  12
GLU A  34
LEU A  19
LEU A  37
LEU A  71
 None
 0.99A 4wg0C-2jzkA:
undetectable
4wg0D-2jzkA:
undetectable
4wg0E-2jzkA:
undetectable		 4wg0C-2jzkA:
19.05
4wg0D-2jzkA:
19.05
4wg0E-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  37
LEU A  71
GLU A  34
LEU A  19
LEU A  12
 None
 0.96A 4wg0F-2jzkA:
undetectable
4wg0G-2jzkA:
undetectable
4wg0H-2jzkA:
undetectable		 4wg0F-2jzkA:
19.05
4wg0G-2jzkA:
19.05
4wg0H-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  12
GLU A  34
LEU A  19
LEU A  37
LEU A  71
 None
 0.98A 4wg0E-2jzkA:
undetectable
4wg0F-2jzkA:
undetectable
4wg0G-2jzkA:
undetectable		 4wg0E-2jzkA:
19.05
4wg0F-2jzkA:
19.05
4wg0G-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  12
GLU A  34
LEU A  19
LEU A  37
LEU A  71
 None
 0.97A 4wg0G-2jzkA:
undetectable
4wg0H-2jzkA:
undetectable
4wg0I-2jzkA:
undetectable		 4wg0G-2jzkA:
19.05
4wg0H-2jzkA:
19.05
4wg0I-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  37
LEU A  71
GLU A  34
LEU A  19
LEU A  12
 None
 1.01A 4wg0J-2jzkA:
undetectable
4wg0K-2jzkA:
undetectable
4wg0L-2jzkA:
undetectable		 4wg0J-2jzkA:
19.05
4wg0K-2jzkA:
19.05
4wg0L-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  12
GLU A  34
LEU A  19
LEU A  37
LEU A  71
 None
 1.02A 4wg0I-2jzkA:
undetectable
4wg0J-2jzkA:
undetectable
4wg0K-2jzkA:
undetectable		 4wg0I-2jzkA:
19.05
4wg0J-2jzkA:
19.05
4wg0K-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 11 LEU A  12
GLU A  34
LEU A  19
LEU A  37
LEU A  71
 None
 1.13A 4wg0K-2jzkA:
undetectable
4wg0L-2jzkA:
undetectable
4wg0M-2jzkA:
undetectable		 4wg0K-2jzkA:
19.05
4wg0L-2jzkA:
19.05
4wg0M-2jzkA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X61_A_SAMA701_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
5)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 12 LEU A  71
GLY A  42
GLY A  51
LEU A  48
CYH A  73
 None
 1.19A 4x61A-2jzkA:
undetectable		 4x61A-2jzkA:
10.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 2jzk CYANOVIRIN-N HOMOLOG
(Tuber
borchii) 		5 / 12 SER A   7
ILE A  93
LEU A  37
ALA A  10
LEU A  64
 None
 1.43A 5zwrB-2jzkA:
undetectable		 5zwrB-2jzkA:
13.84