SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jzl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 2jzl CYANOVIRIN-N HOMOLOG
(Neurospora
crassa) 		4 / 8 ASP A  63
LEU A  78
ASP A  93
THR A  58
 None
 0.98A 1rmtD-2jzlA:
undetectable		 1rmtD-2jzlA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_D_BEZD194_0
(PUTATIVE KINASE)		 2jzl CYANOVIRIN-N HOMOLOG
(Neurospora
crassa) 		4 / 5 ILE A  20
ARG A  15
ARG A  18
ASP A  40
 None
 1.10A 2rhmD-2jzlA:
undetectable		 2rhmD-2jzlA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 2jzl CYANOVIRIN-N HOMOLOG
(Neurospora
crassa) 		4 / 8 ALA A  80
GLY A  44
VAL A  14
ILE A  64
 None
 0.73A 4ll3A-2jzlA:
undetectable		 4ll3A-2jzlA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZX_A_9F2A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2jzl CYANOVIRIN-N HOMOLOG
(Neurospora
crassa) 		4 / 8 PHE A 107
GLN A  41
ILE A  42
GLY A  54
 None
 1.00A 5nzxA-2jzlA:
undetectable		 5nzxA-2jzlA:
13.51