SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jzn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.91A 1v55N-2jznA:
undetectable
1v55W-2jznA:
undetectable		 1v55N-2jznA:
15.94
1v55W-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.91A 2eijN-2jznA:
undetectable
2eijW-2jznA:
undetectable		 2eijN-2jznA:
15.94
2eijW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.91A 2eilN-2jznA:
undetectable
2eilW-2jznA:
undetectable		 2eilN-2jznA:
15.94
2eilW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.93A 2einA-2jznA:
undetectable
2einJ-2jznA:
undetectable		 2einA-2jznA:
15.94
2einJ-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 LEU A  98
LEU A 102
ALA A 118
LEU A 114
 None
 0.87A 2vcvF-2jznA:
undetectable		 2vcvF-2jznA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.86A 3abkA-2jznA:
undetectable
3abkJ-2jznA:
undetectable		 3abkA-2jznA:
15.94
3abkJ-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.86A 3ablN-2jznA:
undetectable
3ablW-2jznA:
undetectable		 3ablN-2jznA:
15.94
3ablW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.86A 3abmN-2jznA:
undetectable
3abmW-2jznA:
undetectable		 3abmN-2jznA:
15.94
3abmW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.87A 3asoN-2jznA:
undetectable
3asoW-2jznA:
undetectable		 3asoN-2jznA:
15.94
3asoW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_2
(DIHYDROFOLATE
REDUCTASE)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 5 ASP A  83
ARG A  79
ILE A  80
VAL A  89
 None
 1.08A 3eigA-2jznA:
undetectable		 3eigA-2jznA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		5 / 11 ASP A  35
ILE A  34
GLY A  32
VAL A  31
VAL A  93
 None
 0.99A 3oxvD-2jznA:
undetectable		 3oxvD-2jznA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		5 / 10 ASP A  35
ILE A  34
GLY A  32
VAL A  31
VAL A  93
 None
 0.95A 3oxwC-2jznA:
undetectable		 3oxwC-2jznA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		5 / 9 ILE A   5
PHE A  64
TYR A  49
LEU A  65
VAL A  81
 None
 1.22A 4g1bC-2jznA:
undetectable		 4g1bC-2jznA:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_1
(PROTEASE PR5-SQV)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		5 / 9 ALA A  14
ASP A  35
ILE A  34
GLY A  32
ILE A   5
 None
 1.29A 5kr2A-2jznA:
undetectable		 5kr2A-2jznA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.86A 5xdxN-2jznA:
undetectable
5xdxW-2jznA:
undetectable		 5xdxN-2jznA:
15.94
5xdxW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.88A 5zcpN-2jznA:
undetectable
5zcpW-2jznA:
undetectable		 5zcpN-2jznA:
15.94
5zcpW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		4 / 8 ILE A   3
LEU A 114
PHE A 111
LEU A  65
 None
 0.89A 5zcqN-2jznA:
undetectable
5zcqW-2jznA:
undetectable		 5zcqN-2jznA:
15.94
5zcqW-2jznA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)		 2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		3 / 3 TYR A  87
ALA A   4
LEU A  53
 None
 0.57A 6d9kF-2jznA:
4.2		 6d9kF-2jznA:
10.08