SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2jzx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JGS_A_SALA256_1
(MULTIPLE ANTIBIOTIC
RESISTANCE PROTEIN
MARR)		 2jzx POLY(RC)-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 7 VAL A 164
THR A  65
LEU A  14
VAL A 159
 None
 0.86A 1jgsA-2jzxA:
undetectable		 1jgsA-2jzxA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 2jzx POLY(RC)-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 12 ILE A 156
ILE A 155
LEU A  79
ILE A  83
MET A  20
 None
 1.15A 1xzxX-2jzxA:
undetectable		 1xzxX-2jzxA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 2jzx POLY(RC)-BINDING
PROTEIN 2
(Homo
sapiens) 		4 / 7 VAL A 159
ILE A  16
ILE A  68
ALA A  71
 None
 0.89A 4lv9B-2jzxA:
undetectable		 4lv9B-2jzxA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2jzx POLY(RC)-BINDING
PROTEIN 2
(Homo
sapiens) 		5 / 10 ALA A 149
PHE A  72
ILE A  76
ILE A 156
VAL A 159
 None
 1.18A 5nukA-2jzxA:
undetectable		 5nukA-2jzxA:
21.52