SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_D_SAMD603_0
(HYPOTHETICAL PROTEIN)		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 12 ILE X  54
GLY X  74
GLY X  71
ALA X  58
VAL X  76
 None
 1.14A 2yvlD-2k0dX:
undetectable		 2yvlD-2k0dX:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 9 GLY X  69
GLY X  70
ASN X  64
GLU X  78
ILE X  75
 None
 1.23A 3owxA-2k0dX:
undetectable		 3owxA-2k0dX:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_B_XRAB233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 11 GLY X  69
GLY X  70
ASN X  64
GLU X  78
ILE X  75
 None
 1.29A 3owxA-2k0dX:
undetectable
3owxB-2k0dX:
undetectable		 3owxA-2k0dX:
19.05
3owxB-2k0dX:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		4 / 8 ASP X   9
SER X   8
GLY X  94
GLN X  93
 None
 0.88A 4af0A-2k0dX:
undetectable		 4af0A-2k0dX:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		4 / 7 GLY X  69
GLY X  70
ASN X  64
GLU X  78
 None
 1.11A 4fgkB-2k0dX:
undetectable		 4fgkB-2k0dX:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		4 / 5 GLY X  69
GLY X  70
ASN X  64
GLU X  78
 None
 1.01A 4fglC-2k0dX:
undetectable		 4fglC-2k0dX:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 6 GLY X  69
GLY X  70
ASN X  64
GLU X  78
ILE X  75
 None
 1.31A 4fglD-2k0dX:
undetectable		 4fglD-2k0dX:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_B_DM2B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2k0d COLICIN-E7 IMMUNITY
PROTEIN
(Escherichia
coli) 		5 / 11 GLY X  69
GLY X  70
ASN X  64
GLU X  78
ILE X  75
 None
 1.23A 4zvmA-2k0dX:
undetectable
4zvmB-2k0dX:
undetectable		 4zvmA-2k0dX:
18.70
4zvmB-2k0dX:
18.70