SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k0r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_G_PZIG801_0 (GLUTAMATE RECEPTOR 2)	2k0r	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD (Neisseria meningitidis)	3 / 3	PRO A 84 SER A 57 ASN A 27	None	0.90A	3lslG-2k0rA: undetectable	3lslG-2k0rA: 21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SO9_A_017A100_1 (HIV-1 PROTEASE)	2k0r	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD (Neisseria meningitidis)	5 / 8	GLY A 25 ALA A 22 ASP A 23 GLY A 120 ILE A 118	None	1.21A	3so9A-2k0rA: undetectable	3so9A-2k0rA: 18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EM2_A_SALA502_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349)	2k0r	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD (Neisseria meningitidis)	4 / 8	TYR A 93 THR A 47 VAL A 28 VAL A 26	None	0.89A	4em2A-2k0rA: undetectable	4em2A-2k0rA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YSH_B_GLYB401_0 (GLYCINE OXIDASE)	2k0r	THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD (Neisseria meningitidis)	4 / 6	PHE A 15 GLY A 101 TYR A 36 ALA A 103	None	1.21A	4yshB-2k0rA: undetectable	4yshB-2k0rA: 17.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3LSL_G_PZIG801_0","GLUTAMATE RECEPTOR 2","2k0r","THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD","Neisseria meningitidis",3,"PRO A  84;SER A  57;ASN A  27","None","0.90A","3lslG-2k0rA:undetectable","3lslG-2k0rA:21.28"],["3SO9_A_017A100_1","HIV-1 PROTEASE","2k0r","THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD","Neisseria meningitidis",5,"GLY A  25;ALA A  22;ASP A  23;GLY A 120;ILE A 118","None","1.21A","3so9A-2k0rA:undetectable","3so9A-2k0rA:18.03"],["4EM2_A_SALA502_1","UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR SAR2349","2k0r","THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD","Neisseria meningitidis",4,"TYR A  93;THR A  47;VAL A  28;VAL A  26","None","0.89A","4em2A-2k0rA:undetectable","4em2A-2k0rA:19.53"],["4YSH_B_GLYB401_0","GLYCINE OXIDASE","2k0r","THIOL:DISULFIDE INTERCHANGE PROTEIN DSBD","Neisseria meningitidis",4,"PHE A  15;GLY A 101;TYR A  36;ALA A 103","None","1.21A","4yshB-2k0rA:undetectable","4yshB-2k0rA:17.72"]]