SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k0z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 2k0z UNCHARACTERIZED
PROTEIN HP1203
(Helicobacter
pylori) 		4 / 7 ALA A   6
LYS A  74
LEU A  70
ALA A  73
 None
 0.92A 1sn0B-2k0zA:
undetectable
1sn0D-2k0zA:
undetectable		 1sn0B-2k0zA:
18.84
1sn0D-2k0zA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 2k0z UNCHARACTERIZED
PROTEIN HP1203
(Helicobacter
pylori) 		4 / 7 LYS A  74
LEU A  70
ALA A  73
ALA A   6
 None
 0.97A 1sn0B-2k0zA:
undetectable
1sn0D-2k0zA:
undetectable		 1sn0B-2k0zA:
18.84
1sn0D-2k0zA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2k0z UNCHARACTERIZED
PROTEIN HP1203
(Helicobacter
pylori) 		4 / 8 ASP A  43
ASN A  42
GLU A  24
GLU A  45
 None
 0.91A 4feuD-2k0zA:
undetectable		 4feuD-2k0zA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2k0z UNCHARACTERIZED
PROTEIN HP1203
(Helicobacter
pylori) 		4 / 7 ASP A  43
ASN A  42
GLU A  24
GLU A  45
 None
 0.92A 4fevB-2k0zA:
undetectable		 4fevB-2k0zA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2k0z UNCHARACTERIZED
PROTEIN HP1203
(Helicobacter
pylori) 		4 / 7 ASP A  43
ASN A  42
GLU A  24
GLU A  45
 None
 0.97A 4fewB-2k0zA:
undetectable		 4fewB-2k0zA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2k0z UNCHARACTERIZED
PROTEIN HP1203
(Helicobacter
pylori) 		4 / 8 ASP A  43
ASN A  42
GLU A  24
GLU A  45
 None
 0.91A 4gkhD-2k0zA:
undetectable		 4gkhD-2k0zA:
15.75