SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		4 / 6 ASN A  71
SER A  10
ASN A   8
THR A  18
 None
 1.12A 1h7xA-2k24A:
undetectable		 1h7xA-2k24A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		4 / 6 ASN A  71
SER A  10
ASN A   8
THR A  18
 None
 1.14A 1h7xB-2k24A:
undetectable		 1h7xB-2k24A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		4 / 6 ASN A  71
SER A  10
ASN A   8
THR A  18
 None
 1.13A 1h7xC-2k24A:
undetectable		 1h7xC-2k24A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		4 / 6 ASN A  71
SER A  10
ASN A   8
THR A  18
 None
 1.12A 1h7xD-2k24A:
undetectable		 1h7xD-2k24A:
7.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IW1_A_ASDA1223_1
(CYTOCHROME P450
CYP125)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		5 / 12 ILE A  37
MET A  77
ILE A  92
VAL A  68
VAL A  70
 None
 1.24A 3iw1A-2k24A:
undetectable		 3iw1A-2k24A:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		4 / 8 ASP A  85
ILE A  84
VAL A  79
GLY A  66
 None
 0.83A 4ac9C-2k24A:
undetectable		 4ac9C-2k24A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 2k24 PUTATIVE
UNCHARACTERIZED
PROTEIN TA0956
(Thermoplasma
acidophilum) 		5 / 9 PHE A  30
SER A  29
LEU A  33
GLU A  32
ILE A  36
 None
 1.36A 6fdyU-2k24A:
undetectable		 6fdyU-2k24A:
15.64