SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k2n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 2k2n SENSOR PROTEIN
(Synechococcus
sp.
RCC307) 		4 / 6 HIS A 159
VAL A 125
LEU A 181
LEU A 127
 None
 0.90A 3kk6A-2k2nA:
undetectable		 3kk6A-2k2nA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 2k2n SENSOR PROTEIN
(Synechococcus
sp.
RCC307) 		3 / 3 ASP A  49
ARG A  73
ALA A 171
 None
 0.73A 3mbgC-2k2nA:
undetectable		 3mbgC-2k2nA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 2k2n SENSOR PROTEIN
(Synechococcus
sp.
RCC307) 		3 / 3 PHE A  45
VAL A 183
GLU A 180
 None
 0.75A 4fvqA-2k2nA:
undetectable		 4fvqA-2k2nA:
19.57