SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k2s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2k2s MICRONEMAL PROTEIN 1
(Toxoplasma
gondii) 		3 / 3 SER A  53
GLY A  52
GLN A  50
 None
 0.49A 3v4tH-2k2sA:
undetectable		 3v4tH-2k2sA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCY_A_DB8A401_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2k2s MICRONEMAL PROTEIN 1
(Toxoplasma
gondii) 		4 / 4 VAL A  62
LEU A  90
ASN A  41
ASP A  44
 None
 1.36A 5vcyA-2k2sA:
undetectable		 5vcyA-2k2sA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 2k2s MICRONEMAL PROTEIN 1
(Toxoplasma
gondii) 		5 / 12 GLY A  74
LEU A  19
VAL A 125
THR A  51
GLY A  52
 None
 1.20A 6gngA-2k2sA:
undetectable		 6gngA-2k2sA:
15.19