SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		4 / 8 PHE A  61
ILE A  53
PHE A  80
VAL A  35
 None
 0.91A 1fslA-2k3dA:
undetectable		 1fslA-2k3dA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		4 / 6 GLU A  16
ASP A  66
TYR A  87
ASP A  88
 None
 1.48A 3pocB-2k3dA:
undetectable		 3pocB-2k3dA:
8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		5 / 12 PHE A  80
PHE A  37
VAL A  35
PHE A  70
ALA A  63
 None
 1.41A 3u9fD-2k3dA:
undetectable
3u9fE-2k3dA:
undetectable		 3u9fD-2k3dA:
15.07
3u9fE-2k3dA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		5 / 12 PHE A  80
PHE A  37
VAL A  35
PHE A  70
ALA A  63
 None
 1.43A 3u9fG-2k3dA:
undetectable
3u9fH-2k3dA:
undetectable		 3u9fG-2k3dA:
15.07
3u9fH-2k3dA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		4 / 8 SER A  73
ILE A  29
LEU A  25
ILE A  53
 None
 0.96A 4dtaB-2k3dA:
2.8		 4dtaB-2k3dA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_2
(BIFUNCTIONAL AAC/APH)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		3 / 3 LEU A  91
ASP A  88
TYR A  87
 None
 0.52A 4qc6B-2k3dA:
undetectable		 4qc6B-2k3dA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 2k3d LIN0334 PROTEIN
(Listeria
innocua) 		4 / 5 ASP A  50
VAL A  21
PHE A  70
GLY A  64
 None
 1.04A 4xp6A-2k3dA:
undetectable		 4xp6A-2k3dA:
9.55