SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k3o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 2k3o TUSP1
(Nephila
antipodiana) 		5 / 10 ALA A  82
ALA A  85
LEU A 107
ALA A  45
SER A  14
 None
 1.03A 2bxgB-2k3oA:
3.2		 2bxgB-2k3oA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 2k3o TUSP1
(Nephila
antipodiana) 		5 / 9 ALA A  78
ALA A  80
GLY A  86
SER A  12
ALA A   8
 None
 1.46A 2vh3A-2k3oA:
0.2		 2vh3A-2k3oA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2k3o TUSP1
(Nephila
antipodiana) 		5 / 10 ILE A  81
ALA A  84
ALA A  85
ALA A  60
ILE A  21
 None
 1.04A 3falA-2k3oA:
undetectable		 3falA-2k3oA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2k3o TUSP1
(Nephila
antipodiana) 		5 / 10 ALA A  46
LEU A 107
ILE A  81
LEU A  15
ILE A  41
 None
 1.08A 3jw3A-2k3oA:
undetectable		 3jw3A-2k3oA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 2k3o TUSP1
(Nephila
antipodiana) 		4 / 4 LEU A  61
ILE A  51
GLY A  59
PHE A  88
 None
 1.03A 4dc3A-2k3oA:
undetectable		 4dc3A-2k3oA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 2k3o TUSP1
(Nephila
antipodiana) 		5 / 10 ALA A  78
LEU A  15
ALA A  16
LEU A 107
ALA A 108
 None
 1.19A 4zbrA-2k3oA:
1.9		 4zbrA-2k3oA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 2k3o TUSP1
(Nephila
antipodiana) 		5 / 12 GLY A  59
GLY A  66
LEU A  43
ASN A  40
ASP A  54
 None
 1.38A 5yn6A-2k3oA:
undetectable		 5yn6A-2k3oA:
18.24