SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k3t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 SER A2455
PHE A2450
SER A2510
ILE A2507
 None
 0.83A 1gm7A-2k3tA:
undetectable
1gm7B-2k3tA:
undetectable		 1gm7A-2k3tA:
19.62
1gm7B-2k3tA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.82A 1p7lC-2k3tA:
undetectable		 1p7lC-2k3tA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.82A 1p7lD-2k3tA:
undetectable		 1p7lD-2k3tA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.82A 1rg9A-2k3tA:
undetectable		 1rg9A-2k3tA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.82A 1rg9B-2k3tA:
undetectable		 1rg9B-2k3tA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.83A 1rg9C-2k3tA:
undetectable		 1rg9C-2k3tA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.83A 1rg9D-2k3tA:
undetectable		 1rg9D-2k3tA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.77A 2obvA-2k3tA:
undetectable		 2obvA-2k3tA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.76A 2p02A-2k3tA:
undetectable		 2p02A-2k3tA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.82A 4kttA-2k3tA:
undetectable		 4kttA-2k3tA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.77A 4kttC-2k3tA:
undetectable		 4kttC-2k3tA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.78A 4ndnA-2k3tA:
undetectable		 4ndnA-2k3tA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.77A 5a1iA-2k3tA:
undetectable		 5a1iA-2k3tA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8S_B_SAMB402_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.77A 5t8sB-2k3tA:
undetectable		 5t8sB-2k3tA:
15.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.79A 6fbnB-2k3tA:
undetectable		 6fbnB-2k3tA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.76A 6fboA-2k3tA:
undetectable		 6fboA-2k3tA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.86A 6fcbA-2k3tA:
undetectable		 6fcbA-2k3tA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 2k3t FILAMIN-A
(Homo
sapiens) 		4 / 8 HIS A2506
PRO A2511
LYS A2500
SER A2463
 None
 0.75A 6fcdA-2k3tA:
undetectable		 6fcdA-2k3tA:
19.79