SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k49'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3F8W_A_ADNA300_1 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	2k49	UPF0339 PROTEIN SO_3888 (Shewanella oneidensis)	5 / 12	SER A 96 TYR A 84 ALA A 21 GLY A 24 ASN A 23	None	1.19A	3f8wA-2k49A: undetectable	3f8wA-2k49A: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3F8W_C_ADNC302_1 (PURINE-NUCLEOSIDE PHOSPHORYLASE)	2k49	UPF0339 PROTEIN SO_3888 (Shewanella oneidensis)	5 / 12	SER A 96 TYR A 84 ALA A 21 GLY A 24 ASN A 23	None	1.20A	3f8wC-2k49A: undetectable	3f8wC-2k49A: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DNU_A_BEZA319_0 (SHKAI2IB)	2k49	UPF0339 PROTEIN SO_3888 (Shewanella oneidensis)	4 / 5	GLN A 47 ILE A 43 ILE A 78 TYR A 5	None	0.99A	5dnuA-2k49A: undetectable	5dnuA-2k49A: 19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DNV_A_BEZA304_0 (SHKAI2IB)	2k49	UPF0339 PROTEIN SO_3888 (Shewanella oneidensis)	4 / 5	GLN A 47 ILE A 43 ILE A 78 TYR A 5	None	1.02A	5dnvA-2k49A: undetectable	5dnvA-2k49A: 19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_G_Z80G401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	2k49	UPF0339 PROTEIN SO_3888 (Shewanella oneidensis)	5 / 10	ILE A 106 ILE A 43 PHE A 17 THR A 103 ASN A 100	None	1.23A	5lg3G-2k49A: undetectable	5lg3G-2k49A: 15.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3F8W_A_ADNA300_1","PURINE-NUCLEOSIDE PHOSPHORYLASE","2k49","UPF0339 PROTEIN SO_3888","Shewanella oneidensis",5,"SER A  96;TYR A  84;ALA A  21;GLY A  24;ASN A  23","None","1.19A","3f8wA-2k49A:undetectable","3f8wA-2k49A:15.22"],["3F8W_C_ADNC302_1","PURINE-NUCLEOSIDE PHOSPHORYLASE","2k49","UPF0339 PROTEIN SO_3888","Shewanella oneidensis",5,"SER A  96;TYR A  84;ALA A  21;GLY A  24;ASN A  23","None","1.20A","3f8wC-2k49A:undetectable","3f8wC-2k49A:15.22"],["5DNU_A_BEZA319_0","SHKAI2IB","2k49","UPF0339 PROTEIN SO_3888","Shewanella oneidensis",4,"GLN A  47;ILE A  43;ILE A  78;TYR A   5","None","0.99A","5dnuA-2k49A:undetectable","5dnuA-2k49A:19.49"],["5DNV_A_BEZA304_0","SHKAI2IB","2k49","UPF0339 PROTEIN SO_3888","Shewanella oneidensis",4,"GLN A  47;ILE A  43;ILE A  78;TYR A   5","None","1.02A","5dnvA-2k49A:undetectable","5dnvA-2k49A:19.49"],["5LG3_G_Z80G401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","2k49","UPF0339 PROTEIN SO_3888","Shewanella oneidensis",5,"ILE A 106;ILE A  43;PHE A  17;THR A 103;ASN A 100","None","1.23A","5lg3G-2k49A:undetectable","5lg3G-2k49A:15.96"]]