SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2k4v UNCHARACTERIZED
PROTEIN PA1076
(Pseudomonas
aeruginosa) 		4 / 6 PHE A  54
ASN A  24
ILE A  23
ASP A  22
 None
 0.95A 1yc2A-2k4vA:
undetectable		 1yc2A-2k4vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_D_NCAD510_0
(NAD-DEPENDENT
DEACETYLASE 2)		 2k4v UNCHARACTERIZED
PROTEIN PA1076
(Pseudomonas
aeruginosa) 		4 / 5 PHE A  54
ASN A  24
ILE A  23
ASP A  22
 None
 0.93A 1yc2D-2k4vA:
undetectable		 1yc2D-2k4vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 2k4v UNCHARACTERIZED
PROTEIN PA1076
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  80
GLN A  21
ALA A  76
ILE A  25
 None
 0.85A 4txnA-2k4vA:
undetectable		 4txnA-2k4vA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 2k4v UNCHARACTERIZED
PROTEIN PA1076
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  80
GLN A  21
ALA A  76
ILE A  25
 None
 0.81A 4txnB-2k4vA:
undetectable		 4txnB-2k4vA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 2k4v UNCHARACTERIZED
PROTEIN PA1076
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  80
GLN A  21
ALA A  76
ILE A  25
 None
 0.83A 4txnC-2k4vA:
undetectable		 4txnC-2k4vA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 2k4v UNCHARACTERIZED
PROTEIN PA1076
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  80
GLN A  21
ALA A  76
ILE A  25
 None
 0.82A 4txnD-2k4vA:
undetectable		 4txnD-2k4vA:
19.52