SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k4z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)
2k4z DSRR
(Allochromatium
vinosum)
3 / 3 ASP A  51
ARG A  27
ASP A  66
None
0.77A 1vptA-2k4zA:
undetectable
1vptA-2k4zA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)
2k4z DSRR
(Allochromatium
vinosum)
3 / 3 PRO A  96
THR A  97
LEU A  91
None
0.79A 3ttrA-2k4zA:
undetectable
3ttrA-2k4zA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)
2k4z DSRR
(Allochromatium
vinosum)
3 / 3 ASP A  51
ARG A  27
ASP A  66
None
0.78A 4fp9D-2k4zA:
undetectable
4fp9D-2k4zA:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)
2k4z DSRR
(Allochromatium
vinosum)
3 / 3 ASP A  51
ARG A  27
ASP A  66
None
0.72A 4fzvA-2k4zA:
undetectable
4fzvA-2k4zA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
2k4z DSRR
(Allochromatium
vinosum)
3 / 3 ASP A  51
ARG A  27
ASP A  66
None
0.79A 5zvgA-2k4zA:
undetectable
5zvgA-2k4zA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)
2k4z DSRR
(Allochromatium
vinosum)
3 / 3 ASP A  51
ARG A  27
ASP A  66
None
0.75A 5zvgB-2k4zA:
undetectable
5zvgB-2k4zA:
16.33