SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k53'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O01_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2k53 A3DK08 PROTEIN
(Ruminiclostridiu
m
thermocellum) 		4 / 8 MET A  28
PHE A  23
ALA A  10
LEU A  13
 None
 1.09A 2o01A-2k53A:
undetectable		 2o01A-2k53A:
5.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 2k53 A3DK08 PROTEIN
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A   3
VAL A  12
THR A  19
ILE A  22
 None
 0.86A 3p4wC-2k53A:
undetectable		 3p4wC-2k53A:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 2k53 A3DK08 PROTEIN
(Ruminiclostridiu
m
thermocellum) 		4 / 8 ILE A   3
VAL A  12
THR A  19
ILE A  22
 None
 0.71A 5mzrE-2k53A:
undetectable		 5mzrE-2k53A:
20.88