SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k5e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA3_C_STRC3001_1 (MINERALOCORTICOID RECEPTOR)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 58 LEU A 61 ASN A 62 LEU A 64 ALA A 65	None	0.85A	1ya3C-2k5eA: undetectable	1ya3C-2k5eA: 12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AA5_B_STRB302_1 (MINERALOCORTICOID RECEPTOR)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 58 ASN A 62 LEU A 64 ALA A 65 MET A 9	None	1.11A	2aa5B-2k5eA: undetectable	2aa5B-2k5eA: 12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_D_SNLD4001_1 (MINERALOCORTICOID RECEPTOR)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 58 ASN A 62 LEU A 64 ALA A 65 MET A 9	None	1.03A	2oaxD-2k5eA: undetectable	2oaxD-2k5eA: 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FN9_A_STRA301_1 (STEROID RECEPTOR 2)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 58 LEU A 61 ASN A 62 LEU A 64 ALA A 65	None	0.80A	4fn9A-2k5eA: undetectable	4fn9A-2k5eA: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FN9_B_STRB301_1 (STEROID RECEPTOR 2)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 58 LEU A 61 ASN A 62 LEU A 64 ALA A 65	None	0.84A	4fn9B-2k5eA: undetectable	4fn9B-2k5eA: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FN9_B_STRB301_1 (STEROID RECEPTOR 2)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 61 ASN A 62 LEU A 64 ALA A 65 MET A 9	None	1.20A	4fn9B-2k5eA: undetectable	4fn9B-2k5eA: 13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LTW_A_STRA301_1 (ANCESTRAL STEROID RECEPTOR 2)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	6 / 12	LEU A 58 LEU A 61 ASN A 62 LEU A 64 ALA A 65 MET A 9	None	1.24A	4ltwA-2k5eA: undetectable	4ltwA-2k5eA: 13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y0Q_A_PX9A201_0 (BETA-LACTOGLOBULIN)	2k5e	UNCHARACTERIZED PROTEIN (Methanocaldococc us jannaschii)	5 / 12	LEU A 15 VAL A 21 LEU A 52 ILE A 57 LEU A 61	None	1.09A	4y0qA-2k5eA: undetectable	4y0qA-2k5eA: 17.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YA3_C_STRC3001_1","MINERALOCORTICOID RECEPTOR","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  58;LEU A  61;ASN A  62;LEU A  64;ALA A  65","None","0.85A","1ya3C-2k5eA:undetectable","1ya3C-2k5eA:12.55"],["2AA5_B_STRB302_1","MINERALOCORTICOID RECEPTOR","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  58;ASN A  62;LEU A  64;ALA A  65;MET A   9","None","1.11A","2aa5B-2k5eA:undetectable","2aa5B-2k5eA:12.36"],["2OAX_D_SNLD4001_1","MINERALOCORTICOID RECEPTOR","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  58;ASN A  62;LEU A  64;ALA A  65;MET A   9","None","1.03A","2oaxD-2k5eA:undetectable","2oaxD-2k5eA:12.50"],["4FN9_A_STRA301_1","STEROID RECEPTOR 2","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  58;LEU A  61;ASN A  62;LEU A  64;ALA A  65","None","0.80A","4fn9A-2k5eA:undetectable","4fn9A-2k5eA:13.62"],["4FN9_B_STRB301_1","STEROID RECEPTOR 2","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  58;LEU A  61;ASN A  62;LEU A  64;ALA A  65","None","0.84A","4fn9B-2k5eA:undetectable","4fn9B-2k5eA:13.62"],["4FN9_B_STRB301_1","STEROID RECEPTOR 2","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  61;ASN A  62;LEU A  64;ALA A  65;MET A   9","None","1.20A","4fn9B-2k5eA:undetectable","4fn9B-2k5eA:13.62"],["4LTW_A_STRA301_1","ANCESTRAL STEROID RECEPTOR 2","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",6,"LEU A  58;LEU A  61;ASN A  62;LEU A  64;ALA A  65;MET A   9","None","1.24A","4ltwA-2k5eA:undetectable","4ltwA-2k5eA:13.73"],["4Y0Q_A_PX9A201_0","BETA-LACTOGLOBULIN","2k5e","UNCHARACTERIZED PROTEIN","Methanocaldococcus jannaschii",5,"LEU A  15;VAL A  21;LEU A  52;ILE A  57;LEU A  61","None","1.09A","4y0qA-2k5eA:undetectable","4y0qA-2k5eA:17.68"]]