SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k6m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 2k6m SUPERVILLIN
(Homo
sapiens) 		4 / 7 ASP S  46
TYR S  41
TYR S  19
PRO S  20
 None
 1.46A 2q6kA-2k6mS:
undetectable		 2q6kA-2k6mS:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2k6m SUPERVILLIN
(Homo
sapiens) 		3 / 3 ASP S  34
GLU S  31
GLY S  32
 None
 0.70A 3w9tA-2k6mS:
undetectable		 3w9tA-2k6mS:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2k6m SUPERVILLIN
(Homo
sapiens) 		4 / 5 LYS S  70
LEU S  75
GLU S  39
LEU S  42
 None
 1.27A 4k4yA-2k6mS:
undetectable		 4k4yA-2k6mS:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2k6m SUPERVILLIN
(Homo
sapiens) 		4 / 4 LYS S  70
LEU S  75
GLU S  39
LEU S  42
 None
 1.28A 4k4yE-2k6mS:
undetectable		 4k4yE-2k6mS:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 2k6m SUPERVILLIN
(Homo
sapiens) 		4 / 5 LYS S  70
LEU S  75
GLU S  39
LEU S  42
 None
 1.25A 4k4yI-2k6mS:
undetectable		 4k4yI-2k6mS:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 2k6m SUPERVILLIN
(Homo
sapiens) 		3 / 3 GLU S  31
ASP S  34
PRO S  35
 None
 0.72A 6berA-2k6mS:
undetectable		 6berA-2k6mS:
25.00