SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)
2k6v PUTATIVE CYTOCHROME
C OXIDASE ASSEMBLY
PROTEIN

(Thermus
thermophilus)
4 / 5 TYR A  93
LEU A  55
VAL A  80
ASP A  85
None
1.47A 1dz6A-2k6vA:
undetectable
1dz6A-2k6vA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)
2k6v PUTATIVE CYTOCHROME
C OXIDASE ASSEMBLY
PROTEIN

(Thermus
thermophilus)
5 / 12 LEU A  21
GLY A  43
PHE A  41
TYR A 122
ALA A 115
None
1.30A 5j7wC-2k6vA:
undetectable
5j7wC-2k6vA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D9K_F_ACTF802_0
(UNCHARACTERIZED
PROTEIN)
2k6v PUTATIVE CYTOCHROME
C OXIDASE ASSEMBLY
PROTEIN

(Thermus
thermophilus)
3 / 3 TYR A 153
ALA A  61
LEU A 168
None
0.56A 6d9kF-2k6vA:
undetectable
6d9kF-2k6vA:
13.49