SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k7b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OCT_A_1N1A663_2 (TYROSINE-PROTEIN KINASE BTK)	2k7b	CALCIUM-BINDING PROTEIN 1 (Homo sapiens)	4 / 5	PHE A 31 ILE A 24 MET A 51 ASN A 49	None	1.16A	3octA-2k7bA: undetectable	3octA-2k7bA: 13.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A7T_A_5FWA1001_1 (SUPEROXIDE DISMUTASE [CU-ZN])	2k7b	CALCIUM-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	ASP A 39 LYS A 38 ASP A 35	MG A 601 (-3.5A) None MG A 601 (-3.3A)	0.76A	4a7tA-2k7bA: undetectable	4a7tA-2k7bA: 22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_A_SAMA401_1 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	2k7b	CALCIUM-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	ASP A 46 ARG A 45 ASP A 39	None None MG A 601 (-3.5A)	0.85A	5zvgA-2k7bA: undetectable	5zvgA-2k7bA: 10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_B_SAMB401_1 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	2k7b	CALCIUM-BINDING PROTEIN 1 (Homo sapiens)	3 / 3	ASP A 46 ARG A 45 ASP A 39	None None MG A 601 (-3.5A)	0.89A	5zvgB-2k7bA: undetectable	5zvgB-2k7bA: 10.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OCT_A_1N1A663_2","TYROSINE-PROTEIN KINASE BTK","2k7b","CALCIUM-BINDING PROTEIN 1","Homo sapiens",4,"PHE A  31;ILE A  24;MET A  51;ASN A  49","None","1.16A","3octA-2k7bA:undetectable","3octA-2k7bA:13.79"],["4A7T_A_5FWA1001_1","SUPEROXIDE DISMUTASE [CU-ZN]","2k7b","CALCIUM-BINDING PROTEIN 1","Homo sapiens",3,"ASP A  39;LYS A  38;ASP A  35"," MG A 601 (-3.5A);None; MG A 601 (-3.3A)","0.76A","4a7tA-2k7bA:undetectable","4a7tA-2k7bA:22.39"],["5ZVG_A_SAMA401_1","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","2k7b","CALCIUM-BINDING PROTEIN 1","Homo sapiens",3,"ASP A  46;ARG A  45;ASP A  39","None;None; MG A 601 (-3.5A)","0.85A","5zvgA-2k7bA:undetectable","5zvgA-2k7bA:10.68"],["5ZVG_B_SAMB401_1","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","2k7b","CALCIUM-BINDING PROTEIN 1","Homo sapiens",3,"ASP A  46;ARG A  45;ASP A  39","None;None; MG A 601 (-3.5A)","0.89A","5zvgB-2k7bA:undetectable","5zvgB-2k7bA:10.68"]]