SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2k7d CALCIUM-BINDING
PROTEIN 1
(Homo
sapiens) 		6 / 11 PHE A 111
ILE A 119
LEU A 124
MET A 128
LEU A 131
VAL A 148
 None
 1.19A 1dtlA-2k7dA:
8.7		 1dtlA-2k7dA:
21.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2k7d CALCIUM-BINDING
PROTEIN 1
(Homo
sapiens) 		6 / 12 ILE A 119
LEU A 124
MET A 128
LEU A 131
VAL A 156
MET A 165
 None
 1.14A 1lxfC-2k7dA:
7.2		 1lxfC-2k7dA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2k7d CALCIUM-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 5 PHE A 111
LEU A 131
PHE A 161
MET A 165
 None
 1.34A 1wrkB-2k7dA:
9.1		 1wrkB-2k7dA:
39.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 2k7d CALCIUM-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 8 ILE A 119
LEU A 124
VAL A 156
MET A 164
 None
 0.63A 4rjdA-2k7dA:
9.5		 4rjdA-2k7dA:
43.06