SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		5 / 6 LEU A  78
ALA A  16
LEU A 103
SER A 111
SER A  11
 None
 1.41A 1tz8C-2k7hA:
undetectable
1tz8D-2k7hA:
undetectable		 1tz8C-2k7hA:
26.43
1tz8D-2k7hA:
26.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		4 / 5 LEU A 142
ALA A  33
ILE A  30
LYS A 138
 None
 1.07A 2othA-2k7hA:
undetectable		 2othA-2k7hA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		5 / 12 ILE A  30
VAL A  66
LEU A  90
ALA A 139
VAL A 117
 None
 1.19A 3w67C-2k7hA:
undetectable		 3w67C-2k7hA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIX_A_NIMA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		4 / 4 LEU A 142
ALA A  33
ILE A  30
LYS A 138
 None
 1.03A 4eixA-2k7hA:
undetectable		 4eixA-2k7hA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		4 / 8 ALA A  14
PRO A  12
LEU A 150
LEU A 151
 None
 1.14A 5dzkF-2k7hA:
undetectable
5dzkT-2k7hA:
undetectable		 5dzkF-2k7hA:
21.78
5dzkT-2k7hA:
1.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		3 / 3 LYS A  32
LEU A 142
ILE A  55
 None
 0.78A 5kc0A-2k7hA:
undetectable		 5kc0A-2k7hA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_A_RBFA201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 2k7h STRESS-INDUCED
PROTEIN SAM22
(Glycine
max) 		3 / 3 LYS A  32
LEU A 142
ILE A  55
 None
 0.79A 5kc4A-2k7hA:
undetectable		 5kc4A-2k7hA:
23.44