SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k7l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_E_4LEE401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2k7l GENERAL
TRANSCRIPTION FACTOR
IIF SUBUNIT 1
(Homo
sapiens) 		5 / 10 LEU A 463
THR A 470
LEU A 473
LEU A 497
LEU A 500
 None
 1.03A 4z91A-2k7lA:
0.0
4z91B-2k7lA:
undetectable
4z91C-2k7lA:
undetectable
4z91D-2k7lA:
undetectable
4z91E-2k7lA:
undetectable		 4z91A-2k7lA:
12.50
4z91B-2k7lA:
12.50
4z91C-2k7lA:
12.50
4z91D-2k7lA:
12.50
4z91E-2k7lA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 2k7l GENERAL
TRANSCRIPTION FACTOR
IIF SUBUNIT 1
(Homo
sapiens) 		5 / 8 ARG A 460
ALA A 458
LEU A 463
LEU A 493
LEU A 473
 None
 1.44A 5jqbA-2k7lA:
undetectable
5jqbB-2k7lA:
undetectable		 5jqbA-2k7lA:
12.77
5jqbB-2k7lA:
13.69