SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k7n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		6 / 12 PHE A 112
GLY A 109
GLY A  71
LEU A  98
ASN A 102
ALA A 103
 None
 1.50A 3av6A-2k7nA:
undetectable		 3av6A-2k7nA:
9.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		4 / 4 SER A 182
GLY A 181
GLY A 172
GLY A 177
 None
 0.88A 3bogB-2k7nA:
undetectable
3bogD-2k7nA:
undetectable		 3bogB-2k7nA:
undetectable
3bogD-2k7nA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		4 / 6 ILE A 136
LEU A 198
ARG A 131
THR A  93
 None
 1.19A 3wg7A-2k7nA:
undetectable
3wg7J-2k7nA:
undetectable		 3wg7A-2k7nA:
15.18
3wg7J-2k7nA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 PRO A 197
PRO A 189
LEU A  90
ILE A 128
ALA A 117
 None
 1.35A 4a83A-2k7nA:
undetectable		 4a83A-2k7nA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 PHE A 112
ALA A 101
MET A 100
LEU A  25
GLY A  74
 None
 1.23A 4kykA-2k7nA:
undetectable
4kykB-2k7nA:
undetectable		 4kykA-2k7nA:
20.75
4kykB-2k7nA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		4 / 5 ARG A  72
THR A  68
THR A  70
ASP A  66
 None
 1.41A 4qwpB-2k7nA:
undetectable		 4qwpB-2k7nA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 GLY A  65
PHE A  39
TYR A  78
ILE A  77
ALA A  75
 None
 0.99A 5n0sA-2k7nA:
undetectable		 5n0sA-2k7nA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 GLY A  65
PHE A  39
TYR A  78
ILE A  77
ALA A  75
 None
 0.97A 5n0tA-2k7nA:
undetectable		 5n0tA-2k7nA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 GLY A  65
PHE A  39
TYR A  78
ILE A  77
ALA A  75
 None
 0.96A 5n0tB-2k7nA:
undetectable		 5n0tB-2k7nA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 GLY A  65
PHE A  39
TYR A  78
ILE A  77
ALA A  75
 None
 0.98A 5n0wB-2k7nA:
undetectable		 5n0wB-2k7nA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 GLY A  65
PHE A  39
TYR A  78
ILE A  77
ALA A  75
 None
 0.99A 5n0xA-2k7nA:
undetectable		 5n0xA-2k7nA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2k7n PEPTIDYL-PROLYL
CIS-TRANS
ISOMERASE-LIKE 1
(Homo
sapiens) 		5 / 12 GLY A  65
PHE A  39
TYR A  78
ILE A  77
ALA A  75
 None
 0.98A 5n4iA-2k7nA:
undetectable		 5n4iA-2k7nA:
17.66