SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 2k7q FILAMIN-A
(Homo
sapiens) 		4 / 8 VAL A2030
VAL A2007
ILE A2009
LEU A1983
 None
 0.88A 1igxA-2k7qA:
undetectable		 1igxA-2k7qA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y80_A_IREA402_0
(CYCLIN-G-ASSOCIATED
KINASE)		 2k7q FILAMIN-A
(Homo
sapiens) 		5 / 11 VAL A2090
ILE A2092
ASN A2093
THR A2094
ILE A2116
 None
 1.27A 5y80A-2k7qA:
undetectable		 5y80A-2k7qA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 2k7q FILAMIN-A
(Homo
sapiens) 		4 / 7 VAL A2050
LEU A2057
GLY A2079
LEU A2082
 None
 0.65A 6eu9D-2k7qA:
undetectable		 6eu9D-2k7qA:
17.99