SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k8g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 2k8g POLYADENYLATE-BINDIN
G PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 106
ILE A 110
MET A 158
PHE A 145
VAL A 143
 None
 1.04A 2ygpA-2k8gA:
undetectable		 2ygpA-2k8gA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 2k8g POLYADENYLATE-BINDIN
G PROTEIN 1
(Homo
sapiens) 		6 / 11 PHE A 122
ALA A 150
GLU A 156
ILE A 101
VAL A 143
VAL A 170
 None
 1.49A 3kw4A-2k8gA:
undetectable		 3kw4A-2k8gA:
10.50