SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k8o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 3uboB-2k8oA:
undetectable		 3uboB-2k8oA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 4e3aA-2k8oA:
undetectable		 4e3aA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 4jkuB-2k8oA:
undetectable		 4jkuB-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.02A 4k8pA-2k8oA:
undetectable		 4k8pA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 4k8pB-2k8oA:
undetectable		 4k8pB-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.03A 4k8tA-2k8oA:
undetectable		 4k8tA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.04A 4k93A-2k8oA:
undetectable		 4k93A-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.03A 4k93B-2k8oA:
undetectable		 4k93B-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.02A 4k9cA-2k8oA:
undetectable		 4k9cA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.02A 4k9cB-2k8oA:
undetectable		 4k9cB-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.02A 4k9iA-2k8oA:
undetectable		 4k9iA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.03A 4k9iB-2k8oA:
undetectable		 4k9iB-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 4kadA-2k8oA:
undetectable		 4kadA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.02A 4kadB-2k8oA:
undetectable		 4kadB-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 4lbxA-2k8oA:
undetectable		 4lbxA-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.03A 4lbxB-2k8oA:
undetectable		 4lbxB-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.02A 4lc4A-2k8oA:
undetectable		 4lc4A-2k8oA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 2k8o INTEGRIN ALPHA-L
(Homo
sapiens) 		5 / 12 ILE A  14
ASP A  59
GLY A  56
GLY A  19
LEU A  10
 None
 1.01A 4lc4B-2k8oA:
undetectable		 4lc4B-2k8oA:
11.53