SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k8q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 2k8q PROTEIN SHQ1
(Saccharomyces
cerevisiae) 		3 / 3 PHE A   6
LEU A  96
MET A  39
 None
 0.84A 1mx1D-2k8qA:
undetectable		 1mx1D-2k8qA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2k8q PROTEIN SHQ1
(Saccharomyces
cerevisiae) 		5 / 12 SER A  69
THR A   3
PHE A  42
ILE A  74
ASN A  75
 None
 1.36A 2vdyA-2k8qA:
undetectable		 2vdyA-2k8qA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2k8q PROTEIN SHQ1
(Saccharomyces
cerevisiae) 		4 / 6 GLN A  10
PHE A  53
PRO A  54
LEU A  96
 None
 1.33A 3tgvD-2k8qA:
undetectable		 3tgvD-2k8qA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2k8q PROTEIN SHQ1
(Saccharomyces
cerevisiae) 		5 / 12 SER A  69
THR A   3
PHE A  42
ILE A  74
ASN A  75
 None
 1.42A 4c49B-2k8qA:
undetectable		 4c49B-2k8qA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 2k8q PROTEIN SHQ1
(Saccharomyces
cerevisiae) 		5 / 12 SER A  69
THR A   3
PHE A  42
ILE A  74
ASN A  75
 None
 1.46A 4c49D-2k8qA:
undetectable		 4c49D-2k8qA:
16.67