SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2k9x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT2_A_SAMA301_1
(FIBRILLARIN-LIKE
PRE-RRNA PROCESSING
PROTEIN)		 2k9x UNCHARACTERIZED
PROTEIN
(Trypanosoma
brucei) 		3 / 3 THR A  23
GLU A  94
ASP A  76
 None
 0.82A 1nt2A-2k9xA:
undetectable		 1nt2A-2k9xA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2k9x UNCHARACTERIZED
PROTEIN
(Trypanosoma
brucei) 		5 / 12 LEU A  87
ALA A  77
GLU A  78
LEU A  44
ILE A   7
 None
 1.12A 1s9pD-2k9xA:
undetectable		 1s9pD-2k9xA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_1
(HYPOTHETICAL PROTEIN)		 2k9x UNCHARACTERIZED
PROTEIN
(Trypanosoma
brucei) 		4 / 4 GLU A  94
ASP A  91
ASP A  76
TYR A  85
 None
 0.96A 2yvlA-2k9xA:
0.0		 2yvlA-2k9xA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 2k9x UNCHARACTERIZED
PROTEIN
(Trypanosoma
brucei) 		5 / 12 LEU A  25
ASP A  91
VAL A  93
GLY A  39
VAL A   9
 None
 1.01A 3gguA-2k9xA:
undetectable		 3gguA-2k9xA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 2k9x UNCHARACTERIZED
PROTEIN
(Trypanosoma
brucei) 		5 / 10 LEU A  25
ASP A  91
VAL A  93
GLY A  39
VAL A   9
 None
 1.05A 3nu9B-2k9xA:
undetectable		 3nu9B-2k9xA:
22.22