SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kbf'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P91_B_SAMB2401_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE A)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	5 / 12	TYR A 325 LEU A 324 GLY A 434 ILE A 437 LEU A 350	None	1.11A	1p91B-2kbfA: undetectable	1p91B-2kbfA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RA8_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.45A	1ra8A-2kbfA: undetectable	1ra8A-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RX7_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ALA A 436 LEU A 321 THR A 386 ILE A 385 LEU A 350 ILE A 334	None	1.30A	1rx7A-2kbfA: undetectable	1rx7A-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UWJ_B_BAXB1723_2 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	3 / 3	ILE A 475 ASP A 310 PHE A 439	None	0.54A	1uwjB-2kbfA: undetectable	1uwjB-2kbfA: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C12_C_SPMC1434_1 (NITROALKANE OXIDASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	5 / 12	LEU A 390 ALA A 343 LEU A 346 LEU A 384 VAL A 383	None	1.16A	2c12C-2kbfA: undetectable	2c12C-2kbfA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TQB_A_FOLA2001_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 11	ALA A 436 LEU A 321 THR A 386 ILE A 385 LEU A 350 ILE A 334	None	1.32A	3tqbA-2kbfA: undetectable	3tqbA-2kbfA: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_A_SALA404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 7	ASN A 388 ALA A 338 PRO A 408 ALA A 411	None	0.91A	3twpA-2kbfA: 2.0	3twpA-2kbfA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_B_SALB404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 7	ASN A 388 ALA A 338 PRO A 408 ALA A 411	None	0.93A	3twpB-2kbfA: undetectable	3twpB-2kbfA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_C_SALC404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 7	ASN A 388 ALA A 338 PRO A 408 ALA A 411	None	0.94A	3twpC-2kbfA: undetectable	3twpC-2kbfA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_D_SALD404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	4 / 5	ASN A 388 ALA A 338 PRO A 408 ALA A 411	None	0.91A	3twpD-2kbfA: undetectable	3twpD-2kbfA: 18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FHB_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.44A	4fhbA-2kbfA: undetectable	4fhbA-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I13_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.41A	4i13A-2kbfA: undetectable	4i13A-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJK_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.48A	4kjkA-2kbfA: undetectable	4kjkA-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJL_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.42A	4kjlA-2kbfA: undetectable	4kjlA-2kbfA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P3Q_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.46A	4p3qA-2kbfA: undetectable	4p3qA-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PSS_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	6 / 12	ILE A 335 ALA A 436 THR A 398 ILE A 394 LEU A 390 ILE A 334	None	1.45A	4pssA-2kbfA: undetectable	4pssA-2kbfA: 22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNU_C_QDNC602_1 (CYTOCHROME P450 2D6)	2kbf	ATP-DEPENDENT RNA HELICASE DBP5 (Saccharomyces cerevisiae)	5 / 11	GLY A 348 LEU A 350 GLU A 353 ALA A 315 ASP A 316	None	1.23A	4wnuC-2kbfA: undetectable	4wnuC-2kbfA: 16.08