SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kbg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWE_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 7 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 0.99A 1lweA-2kbgA:
undetectable		 1lweA-2kbgA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KAW_A_SUZA91_1
(SEGMENT POLARITY
PROTEIN DISHEVELLED
HOMOLOG DVL-1)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		5 / 11 PHE A  18
GLY A  10
SER A  21
ILE A  22
VAL A  73
 None
 1.00A 2kawA-2kbgA:
undetectable		 2kawA-2kbgA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 8 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 0.96A 3v81C-2kbgA:
undetectable		 3v81C-2kbgA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 7 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 1.06A 4b3qA-2kbgA:
undetectable		 4b3qA-2kbgA:
12.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 8 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 1.02A 4puoC-2kbgA:
undetectable		 4puoC-2kbgA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 8 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 0.99A 4pwdC-2kbgA:
undetectable		 4pwdC-2kbgA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2kbg NEURAL CELL ADHESION
MOLECULE 2
(Homo
sapiens) 		4 / 8 LEU A  20
VAL A  37
TYR A  71
TYR A  39
 None
 0.96A 4q0bA-2kbgA:
undetectable		 4q0bA-2kbgA:
11.93