SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 2kbo DNA DC->DU-EDITING
ENZYME APOBEC-3G
(Homo
sapiens) 		5 / 11 HIS A  67
LEU A 181
SER A  94
CYH A  98
ILE A 124
 ZN  A 250 ( 3.1A)
None
None
ZN  A 250 ( 2.3A)
None
 1.39A 1ee2B-2kboA:
undetectable		 1ee2B-2kboA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 2kbo DNA DC->DU-EDITING
ENZYME APOBEC-3G
(Homo
sapiens) 		3 / 3 THR A 121
SER A  96
PHE A  72
 None
 0.72A 3d4sA-2kboA:
undetectable		 3d4sA-2kboA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 2kbo DNA DC->DU-EDITING
ENZYME APOBEC-3G
(Homo
sapiens) 		5 / 12 LEU A 138
GLU A 104
LEU A  70
ILE A 145
LEU A 117
 None
 1.23A 3olsB-2kboA:
undetectable		 3olsB-2kboA:
19.68