SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2kbx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 2kbx INTEGRIN-LINKED
PROTEIN KINASE
LIM AND SENESCENT
CELL
ANTIGEN-LIKE-CONTAIN
ING DOMAIN PROTEIN 1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG B  56
SER A  76
TYR B  58
 None
 1.01A 2q2hA-2kbxB:
undetectable
2q2hB-2kbxB:
undetectable		 2q2hA-2kbxB:
18.75
2q2hB-2kbxB:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 2kbx INTEGRIN-LINKED
PROTEIN KINASE
(Homo
sapiens) 		4 / 6 LEU A 119
ALA A 124
THR A  69
ASN A  97
 None
 0.94A 6f88A-2kbxA:
undetectable		 6f88A-2kbxA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 2kbx INTEGRIN-LINKED
PROTEIN KINASE
(Homo
sapiens) 		5 / 12 ASP A  68
LEU A 119
SER A  76
ALA A  74
ASP A  92
 None
 1.07A 6n91A-2kbxA:
undetectable		 6n91A-2kbxA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 2kbx INTEGRIN-LINKED
PROTEIN KINASE
(Homo
sapiens) 		5 / 12 ASP A  68
LEU A 119
SER A  76
ALA A  74
ASP A  92
 None
 1.07A 6n91B-2kbxA:
undetectable		 6n91B-2kbxA:
20.25